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Original Article
Epidemiologic study of Kawasaki disease in 6 months old and younger infants
Yong Won Park, Ji Whan Han, In Sook Park, Chang Hwi Kim, Sung Ho Cha, Jae Sook Ma, Joon Sung Lee, Tae Chan Kwon, Sang Bum Lee, Chul Ho Kim, Heung Jae Lee, Yong Soo Yun
Clin Exp Pediatr. 2008;51(12):1320-1323.   Published online December 15, 2008
Purpose : The aim of this study was to investigate the epidemiologic status of Kawasaki disease (KD) in infants ≤6 months of age. Methods : For the epidemiologic study of KD in Korea, data from 22,674 KD patients were collected from 1997 to 2005 on a 3-year basis by a retrospective survey. From this survey, data of 1,739 KD patients ≤6...
Case Report
Coronary artery fistula associated with single coronary artery
Seong Man Kim, Min Seob Song, Kwang Hyun Cho, Chul Ho Kim
Clin Exp Pediatr. 2008;51(10):1118-1122.   Published online October 15, 2008
A case of a single coronary artery complicated with a coronary artery fistula (CAF) to the right ventricle is extremely rare, and its management strategy and prognosis are not clear. A 5-year-old boy was hospitalized for evaluation of a continuous heart murmur. Transthoracic echocardiography suggested a CAF to the right ventricle, with an enlarged left coronary artery. Cardiac catheterization...
Original Article
Clinical and Epidemiologic Study of Kawasaki Disease in Children 8 Years of Age and Older
Yong Won Park, Ji Whan Han, In Sook Park, Chang Hwi Kim, Sung Ho Cha, Jae Sook Ma, Tae Chan Kwon, Sang Bum Lee, Chul Ho Kim, Heung Jae Lee, Yong Soo Yun
Clin Exp Pediatr. 2005;48(10):1139-1142.   Published online October 15, 2005
Purpose : The aim of this study was to investigate the epidemiologic and clinical profiles of Kawasaki disease(KD) in children 8 years of age and older. Methods : For the epidemiologic study of KD in Korea, data of total 15,692 KD patients were collected from 1994 to 2002 on a 3 year basis, by the retrospective survey. Among them, data of...
Follow-Up Method in Patients with Kawasaki Disease who had No Coronary Artery Abnormalities in the Convalescent Period
Hee Jung Joo, Min Seob Song, Chul Ho Kim
Clin Exp Pediatr. 2005;48(2):165-173.   Published online February 15, 2005
Purpose : We performed the study to evaluate the value of the follow-up echocardiogram performed 6 months to 1 year after the onset of Kawasaki disease(KD), as recommended by American Heart Association(AHA) guidelines, when echocardiograms in the convalescent period were normal. Methods : Patients were selected from 147 cases diagnosed with KD at Pusan Paik hospital from January 2000 to October...
Case Report
A Case of Repeated Ventricular Tachycardia Caused by Cardiac Rhabdomyomas in an Infant with Tuberous Sclerosis
Hee Jung Joo, Min Seob Song, Tae Gyu Hwang, Chul Ho Kim
Clin Exp Pediatr. 2003;46(9):913-917.   Published online September 15, 2003
Cardiac rhabdomyomas are relatively uncommon and associated with tuberous sclerosis in 40-50% cases. We report a 10-month-old infant with tuberous sclerosis who presented with ventricular arrythmias and status epilepticus. There were hypopigmented macules on the body, periventricular calcifications, renal cyst and cardiac rabdomyomas just below the aortic valve. The patient required resection of left ventricular subaortic masses due to sustained...
A Case of Neonatal Atrial Flutter Treated by Propafenone after Fetal Echocardiographic Diagnosis
Kyung Hwa Lee, Chang Woo Ha, Chul Ho Kim, Min Seob Song, Moon Su Sung
Clin Exp Pediatr. 2002;45(7):928-932.   Published online July 15, 2002
Perinatal atrial flutter is a potentially lethal arrhythmia. Management of this disorder is difficult and controversial. Fetal atrial flutter is a serious and life threatening rhythm disorder particulary when it causes hydrops; it may be associated with fetal death or neurological damage. Although the initial episode of flutter may be difficult to control, recurrence of atrial flutter after successful resolution...
Original Article
Hepatitis B Virus Pre-S Gene Mutations in Children with Chronic Hepatitis B Infection
Jae Young Kim, Woo Yeong Chung, Chul Ho Kim
Clin Exp Pediatr. 2000;43(9):1232-1240.   Published online September 15, 2000
Purpose : The envelope of HBV consists of three polypeptides which are encoded in pre-S/S open reading frame. Three translation initiation sites are present within this pre-S/S open reading frame, i.e. pre-S1, pre-S2, and S, allowing the expression of large, middle and small HBs proteins. The pre-S1 is thought to carry the receptor binding site for viral entry into hepatocyte...
Mutations in Hepatitis B Virus Precore and Core Promotor in Children with Chronic Hepatitis B Infection - Comparison Between Vertical and Non-vertical Transmission -
Jin Kuk Kim, Yeong Hong Park, Woo Yeong Chung, Chul Ho Kim
Clin Exp Pediatr. 2000;43(6):779-791.   Published online June 15, 2000
Purpose : The aims of this study were to investigate the frequencies and role of hepatitis B virus(HBV) precore and core promotor mutations in children with chronic hepatitis B infection. Methods : Sera from 46 children with chronic hepatitis B infection were analyzed by direct sequencing of polymerase chain reaction product of HBV DNA. In this study, the patients were divided...
Hepatitis B Virus Precore and Core Promotor Mutations in Children with Chronic Hepatitis B Infection
Woo Yeong Chung, Jin Kuk Kim, Yeong Hoon Kim, Yeong Hong Park, Chul Ho Kim
Clin Exp Pediatr. 1999;42(10):1392-1402.   Published online October 15, 1999
Purpose : The aims of this study were to investigate the frequencies and role of hepatitis B virus(HBV) precore and core promotor mutations in children with chronic hepatitis B infection. Methods : Sera from 31 children with chronic HBV infection were analyzed by direct sequencing of polymerase chain reaction amplification of HBV DNA. Results : Twenty-nine adr type were analyzed. The mutations...
Case Report
A Case of Superior Mesenteric Artery Aneurysm associated with Marfan Syndrome
Ick Ho Sung, Sang Hee Kim, Min Seop Song, Chul Ho Kim
Clin Exp Pediatr. 1998;41(7):984-988.   Published online July 15, 1998
Superior mesenteric artery aneurysm is very rare complication of Marfan syndrome, especially in children. A 11 years old male patient was admitted to the hospital because of fluctuating high fever and diagnosed as infective endocarditis and Marfan syndrome. During antibiotics therapy, fever was slowly decreased but abdominal pain was developed and pulsatile abdominal mass was palpable in the midline of...
Original Article
Effect of Steroid Therapy on Bone Mineral Density in Children with Minimal Change Nephrotic Syndrome
Byeong Hee Son, Woo Yeong Chung, Chul Ho Kim
Clin Exp Pediatr. 1996;39(6):822-828.   Published online June 15, 1996
Purpose : Osteoporosis and growth failure have been known one of the serious side effects of corticosteroid therapy especially in children. This study was designed to evaluate the effect of long-term administration of steroids on bone mineral density(BMD) in children with nephrotic syndrome and its relationship to cumulative steroid dose, the duration of the rapy and sex. Methods : The BMD of...
Case Report
A Case of Idiopathic Crescentic Glomerulonephritis
Jung Keum Park, Sang Il Goo, Woo Yeong Chung, Chul Ho Kim
Clin Exp Pediatr. 1996;39(1):131-135.   Published online January 15, 1996
We experienced a case of idiopathic crescentic glomerulonephritis in a 10-year-old girl who was admitted to our hospital due to gross hematuria and oliguria for 2 months. The diagnosis was based on the rapidly progressive clinical course to chronic renal failure, positive p-ANCA test and light microscopic findings of diffuse crescents formation in about 80% glomeruli of renal tissue obtained...
Original Article
Study on Anti-neutrophil Cytoplasmic Antibodies in Children with Henoch-Schölein Purpura
Shin Jong Lee, Woo Yeong Chung, Chul Ho Kim, Jeong Nyeo Lee
Clin Exp Pediatr. 1995;38(7):970-975.   Published online July 15, 1995
The presence of IgG, IgA and IgM antineutrophil cytoplasmic antibodies(ANCA) were inves-tigated in 32 children with Henoch-Schölein Purpura(HS purpura), in 14 children with HS pur-pura nephritis who were confirrned by renal biopsy and in 12 control children using flow cytom-etry(FASCan, Beckton-Dickinson, Co, USA) and indirect immunofluorescence technique(Sigma Diagnostics, USA). There were no evidence of IgG, IgA or IgM cytoplasmic ANCA(p-ANCA),...
Significance of Urinary Interleukin 6 Level in Mesangial Proliferative Glomerulonephritis in Children
Byeong Ho Kang, No Hyun Kim, Woo Yeong Chung, Chul Ho Kim, Soon Yong Lee
Clin Exp Pediatr. 1994;37(7):900-905.   Published online July 15, 1994
By animal experiments in rat, it has been known that Interleukin-6(IL-6) is secreted from renal mesangial cells and is an autocrine growth factor for the proliferation of mesangial cells. According to these facts, several studies have been tried for its clinical usefulness by measuring their serum or urinary IL-6 in glomerulonephritis patients with mesangial proliferation. The authors measured urinary IL-6...
A case of histiocytic necrotizing lymphadenitis.
Jin Kuk Kim, Jong Bum Shin, Chul Ho Kim, Soon Yong Lee
Clin Exp Pediatr. 1991;34(4):582-586.   Published online April 30, 1991
We experienced a case of histiocytic necrotizing lymphadenitis in a 10-year old male child with complaints of high fever and painful swelling on right cervical area for 11 days. The diagnosis was based on histopathologic findings of right cervical lymph node, clinical features and laboratory findings. A review of literatures was also presented briefly.
A Case of Aplastic Anemia Following hepatitis.
Gae Soon Yeo, Doo Kweon Kim, Chul Ho Kim, Soon Yong Lee
Clin Exp Pediatr. 1990;33(6):864-869.   Published online June 30, 1990
We experienced a case of aplastic anemia following hepatitis in a 4-year-old girl. Pancytopenia was developed during the convalescent period of hepatitis, and it was getting worse, while serial data of liver function test showed improvement. We tried a methylprednisolone pulse therapy, and about 7 months after treatment the CBC findings returned completely normal. She has enjoyed her healthy life during follow-up of over 2...
The Collaborative Clinical Analysis of 985 Cases of Rheumatic Fever and Rheumatic Carditis in Children for 10 Years(1978~1987) in Korea.
Sung Ho Cha, Sang Young Jeong, Du Bong Lee, Kyong Su Lee, Sang Bum Lee, Tae Chan Kwon, Young Chang Tockgo, Chang Sung Sohn, Keun Chan Sohn, Young Jin Hong, Chan Young Kim, Chang Yee Hong, Yong Soo Yun, Jung Yun Choi, Chang Hwi Kim, Chul Ho Kim, Tae Ju Hwang, Jae Suk Ma, Chan Uhul Joo, Kyoo Hwan Rhee, Hahng Lee
Clin Exp Pediatr. 1989;32(12):1621-1631.   Published online December 31, 1989
Acute rheumatic fever and rheumatic carditis were still important disease of the acquired heart disease in children and adults, in spite of improving socioeconomic status in Korea. Recently, many outbreaks of acute rheumatic fever have been reported in the papers from developed countries. We should be aware of such outbreaks of acute rheumatic fever and should pay attention to their treatment of the patients...
A Case of Myelodysplatic Syndrome.
Sun Bok Suh, Chang Ok Soh, Sang Hoon Lee, Chul Ho Kim, Soon Yong Lee
Clin Exp Pediatr. 1989;32(9):1314-1319.   Published online September 30, 1989
We have experienced a case of myelodysplastic syndrome (RAEB) in an 11-year-old boy with the complaints of pallor and petechiae for 1 month. After diagnosis, improvement was remarkable with chemotherapy of low dose cytosine arabinoside but the RAEB was transformed to acute myeloblastic leukemia 4 months after treatmemt. Anti-leukemic therapy was tried but induction of remission was failed and he was died of sepsis...
Case Report
A Case of Endothelial Sinus Tumor of the Vagina.
Moo Young Oh, Chul Hawn Park, Hyun Gi Jung, Tai Gyu Whang, Chul Ho Kim, Soon Yong Lee, Suk Hee Hong
Clin Exp Pediatr. 1984;27(11):1135-1140.   Published online November 30, 1984
We presented a case of endodermal sinus tumor of the vagina in a 17 month-old female baby with the complaints of vaginal blee4ing and difficulty of urinations. Diagnosis was confirmed by the biopsy findings of the tumor tissue from the vagina and the elevated serum alpha-fetoprotein. A review of related literatures was made.
A Case of Chronic Atrial Tachycardia.
Seung Won Park, Moo Young Oh, In Soon Park, Chul Ho Kim, Soon Yong Lee
Clin Exp Pediatr. 1983;26(9):905-908.   Published online September 30, 1983
We report a case of chronic atrial tachycardia in a 8 year-old boy. One year 3 month duration of chronic precordial palpitation is the only complaint on admission. Diagnosis was confirmed with characteristic EKG findings. Digitalis therapy was tried, but in vain. The clinical manifestations have been persistent during follow-up for 1 year 6 months since diagnosis.
A Case of Aplastic Anemia Following Hepatitis.
Woo Yeong Chung, Seung Won Park, In Soon Park, Chul Ho Kim, Soo Yong Lee
Clin Exp Pediatr. 1983;26(8):812-815.   Published online August 31, 1983
We experienced a case of aplastic anemia following hepatitis in a 11-year old male child. He was admitted because of pallor and gum bleedings with an episode of hepatitis 2 months prior to this admission. On admission CBC showed pancytopenia and there was marked hypocellularity of all hematopoietic elements in bone marrow aspiration. Transfusion and treatment with prednisolone and oxymetholone were tried but...
A Case of Pericarditis as a Complication of Meningococcal Meningitis.
Moo Young Oh, Seung Won Park, In Soon Park, Chul Ho Kim, Soon Yong Lee
Clin Exp Pediatr. 1983;26(8):799-802.   Published online August 31, 1983
We report a case of pericarditis as a complication of meningococcal meningitis in a 10-month old male infant. Pericardial effusion developed on the 8th hospital day during penicillin treatment for meningococcal meningitis. He was treated successfully and recovered completely. A review of related literatures was made.
A Case Report of Congenital Hypoplastic Anemia.
Hyun Gi Jung, Tai Gyo Whang, In Soon Park, Chul Ho Kim, Soon Yong Lee
Clin Exp Pediatr. 1983;26(3):279-283.   Published online March 31, 1983
We observed a case of congenital hypoplastic anemia in 22 months old Korean male infant whose clinical and hematologic improvement was achieved by administration of prednisone. A brief review of related literatures was made.
A Case of Pancreatic Pseudocyst.
Tai Gyu Whang, Hyun Gi Jung, In Sun Park, Chul Ho Kim, Soon Yong Lee, Sang Hyo Kim
Clin Exp Pediatr. 1983;26(2):165-169.   Published online February 28, 1983
We observed a case of pancreatic pseudocyst who was an 10 year-old girl with the chief complaints of intermittent abdominal pain and an abdominal mass in left upper quadrant. The cause of pancreatic pseudocyst was idiopathic, and the diagnosis was made by explor- ative laparatomy and biopsy. A brief review of literatures was made.
Original Article
Cat-Scratch Disease.
Tai Gyu Whang, Hyun Gi Jung, Chul Ho Kim, Soon Yong Lee
Clin Exp Pediatr. 1982;25(3):283-288.   Published online March 31, 1982
We observed a case of cat-scratch disease who was an 18-month-old boy with the chief complaint of generalized enlargement of lymphnodes. Clinical manifestations and patholcgic findings of a lymphnode were presented in detail. The diagnosis of cat-scratch disease in this case was made according to the criteria proposed by Carithers et al. and Margileth. A brief review of literature was made.
Case Report
One Cases of Chylus Ascites.
Kyung Hee Yoo, Chul Ho Kim, Myung Hi Shin, Jong Young Lee
Clin Exp Pediatr. 1979;22(1):60-63.   Published online January 15, 1979
A 2-month old female infant was admitted to the department of pediatrics because of abd ominal distension, failure to thrive & constipation, Paracentesis was done & revealed milkyyellowish fluid like chyle. The clinical symptoms, signs & laboratory findings were compatible with chylus ascites.
2 Cases of Fatal Neurological Complications Following D.P.T. Vaccination.
Chul Ho Kim, Kyung Hee Yoo, Myung Hi Shin, Jong Young Lee
Clin Exp Pediatr. 1978;21(12):1154-1158.   Published online December 31, 1978
2 cases of fatal neurological complications following D.P.T. vaccination were presented with a brief review of literature. One case was a 6 mo. Old baby who developed symptoms 5 hrs. after his. 3rd D.P.T. inoculation and expired about 29 hrs. after vaccination. The other case was 5 mo. Old male who developed symptom 3 2/1 days after his 2nd D.P.T....
Original Article
Clinical Studies of Acute Laryng itis Prevailing on January and February of 1976 in Busan.
Bong Jeong Jun, Chul Ho Kim, Myung Hi Shin, Chong Young Lee
Clin Exp Pediatr. 1977;20(1):43-49.   Published online January 31, 1977
This is a clinical study of 44 cases of acute laryngitis treated in the department of pediatric, Wallace Memorial Baptist Hospital from Jan. through Feb. 1976, when influenza was nation wide. We observed following results; 1) Among the 44 sases, 23 cases were male and 21 cases were female. There were no sex differences. 2) Families of 26 cases (60%),...
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